国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Clinical characteristics and prognosis factors analysis for post-operative ptosis of sphenocavernous meningiomas: A single institution study

第一作者:Shuyu Hao

通讯作者:Junting Zhang

Clinical characteristic Complications Prognostic f

基本信息

  • 负责人:Shuyu Hao
  • 数据来源: OTHERS
  • 论文编号:OTHERS20190356
  • 发表时间:2015-04-01

2015-04-01

已发表文章

发表杂志:Clinical Neurology and Neurosurgery

发表类型: Research

影响因子(IF): 1.876

PMID: 25688032 Pubmed原文链接 全文下载

主要研究背景及目的

方法

Forty-nine consecutive SC meningiomas cases that underwent surgery between April 1997 and December 2012 were reviewed. The clinical courses of all patients were recorded. Prognosis factors of post-operative ptosis were evaluated.

结论

Our experience suggests that the most common complication after the SC meningioma surgery is ocular cranial nerve dysfunction, and the only significance factor relative to post-operative ptosis is the level of extension to the cavernous.

主要结果

There were 38 female and 11 male patients. Mean duration of symptoms was 20.9 months. Visual deficit (34.7%) and headache (22.4%) were the most common presenting symptoms. Mean maximum diameter of the tumors on MRI was 5.1 cm. Subtotal resection was achieved in 51.0% of patients. Follow-up data were available for 39 patients, with a mean follow-up of 73.7 months, and four patients died during follow-up period. Of the 35 living patients, 22 (62.9%) lived a normal life. Univariate analyses showed that factors associated with post-operative ptosis included female patient, with primary operation and the cavernous extension in Category 3 of Hirsch' grading, while multivariate regression analyses showed that only the cavernous extension in Category 3 of Hirsch' grading was independently associated with post-operative ptosis.