Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Clinical characteristics and prognosis factors analysis for post-operative ptosis of sphenocavernous meningiomas: A single institution study
First author：Shuyu Hao
Corresponding author：Junting Zhang
essential_information
2015-04-01
Published articles
Journal：Clinical Neurology and Neurosurgery
Publication type: Research
IF(IF): 1.876
PMID: 25688032 Link To Pubmed Full text Download
Background And Purpose
Method
Forty-nine consecutive SC meningiomas cases that underwent surgery between April 1997 and December 2012 were reviewed. The clinical courses of all patients were recorded. Prognosis factors of post-operative ptosis were evaluated.
Conclusion
Our experience suggests that the most common complication after the SC meningioma surgery is ocular cranial nerve dysfunction, and the only significance factor relative to post-operative ptosis is the level of extension to the cavernous.
Main results
There were 38 female and 11 male patients. Mean duration of symptoms was 20.9 months. Visual deficit (34.7%) and headache (22.4%) were the most common presenting symptoms. Mean maximum diameter of the tumors on MRI was 5.1 cm. Subtotal resection was achieved in 51.0% of patients. Follow-up data were available for 39 patients, with a mean follow-up of 73.7 months, and four patients died during follow-up period. Of the 35 living patients, 22 (62.9%) lived a normal life. Univariate analyses showed that factors associated with post-operative ptosis included female patient, with primary operation and the cavernous extension in Category 3 of Hirsch' grading, while multivariate regression analyses showed that only the cavernous extension in Category 3 of Hirsch' grading was independently associated with post-operative ptosis.