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Similar MR imaging characteristics but different pathological changes: a misdiagnosis for Lhermitte-Duclos disease and review of the literature
First author：Shengyue Huang, Guobin Zhang
Corresponding author：Junting Zhang
essential_information
- Person in charge：Shengyue Huang, Guobin Zhang
- Data Sources： OTHERS
- Number of papers：OTHERS20190371
- Published time：2015-06-01
2015-06-01
Published articles
Journal：International Journal of Clinical and Experimental Pathology
Publication type: Case Report
IF(IF): 0.205
PMID: 26261673 Link To Pubmed Full text Download
Background And Purpose
Method
We present a patient who suffered from a normal cerebellum with arachnoid vascular malformation that had imaging characteristics which were indistinguishable from LDD before operation.
Conclusion
This atypical imaging appearance, which could potentially be confused with LDD, may lead to misdiagnosis and inappropriate treatment in the absence of tissue sampling. Thus, this finding suggests that in those patients where images are highly suggestive of LDD but lack other manifestations of Cowden syndrome, biopsy is required and advanced imaging with magnetic resonance spectroscopy (MRS) should be strongly considered.
Main results
This atypical imaging appearance, which could potentially be confused with LDD, may lead to misdiagnosis and inappropriate treatment in the absence of tissue sampling. Thus, this finding suggests that in those patients where images are highly suggestive of LDD but lack other manifestations of Cowden syndrome, biopsy is required and advanced imaging with magnetic resonance spectroscopy (MRS) should be strongly considered.