国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Classification based on mutations of TERT promoter and IDH characterizes subtypes in grade II/III gliomas.

第一作者：Pei Yang, Jinquan Cai

通讯作者：Tao Jiang

grade II/III gliomas IDH mutation TERT promoter

基本信息

2016-08-01

已发表文章

发表杂志：Neuro-Oncology

发表类型: Research Article

影响因子(IF): 12.3

PMID: 26957363 Pubmed原文链接 全文下载

主要研究背景及目的

方法

Here we sequenced TERT promoter mutational status (TERTp-mut) in the DNA of 377 grade II/III gliomas and analyzed the clinical factors, molecular aberrations, and transcriptome profiles

结论

Our results showed that TERTp-mut combined with IDH-mut allowed simple classification of grade II/III gliomas for stratifying patients and clarifying diagnostic accuracy by supplementing standard histopathological criteria.

主要结果