Endovascular Therapy in Acute Ischemic Stroke: Challenges and Transition From Trials to Bedside.
First author:Mayank Goyal
Corresponding author:Michael D Hill
2016-02-01
Journal:Stroke
Publication type: Comments And Opinions
IF(IF): 7.914
PMID: 26742796 Link To Pubmed Full text Download
In this article, we review the current evidence on endovascular therapy in acute ischemic stroke and discuss the major challenges in the implementation of this therapy.
In conclusion, in light of the recent positive trials making endovascular therapy the standard of care for acute ischemic stroke secondary to large vessel occlusion, we present 3 major challenges that need to be addressed. First, effective implementation of trial results across large populations; second, monitoring, encouraging, and approving only the new innovative therapies that result in further improvement in patient outcomes; and third, creating a framework to allow extrapolation of trial results to patient populations that were not tested in the trials. Finally, last but not the least, we wish to stimulate future discussions on increasing accessibility to endovascular therapy in developing nations. We call upon our colleagues in the field to take a proactive and innovative stance in providing guidance and influencing policy through creation of registries or active visualization, allowing feedback for reevaluation of target goals of outcomes