Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Tumor cell-specific chromosomal abnormality in the vascular endothelial cells of anaplastic oligodendroglioma.
First author：Haihui Jiang
Corresponding author：Song Lin
essential_information
- Person in charge：Haihui Jiang
- Data Sources： OTHERS
- Number of papers：OTHERS20190383
- Published time：2016-10-01
2016-10-01
Published articles
Journal：J Neurosurg
Publication type: Research Article
IF(IF): 5.115
PMID: 26771849 Link To Pubmed Full text Download
Background And Purpose
Method
A total of 30 samples from 16 male and 14 female patients (median age of 46.5 years) with a histological diagnosis of primary anaplastic oligodendroglioma (AO) were collected in the study. The immunofluorescence technique was used to identify vascular ECs, and the 1p/19q status was detected with fluorescence in situ hybridization. KaplanMeier plots were compared using the log-rank method.
Conclusion
1p/19q co-deletion and polysomy can be also found in the ECs of AO, which suggests that the ECs are, in part, tumor related and reflect a novel aspect of tumor angiogenesis.