国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Tumor cell-specific chromosomal abnormality in the vascular endothelial cells of anaplastic oligodendroglioma.

第一作者:Haihui Jiang

通讯作者:Song Lin

anaplastic oligodendroglioma; 1p/19q; endothelial 

基本信息

  • 负责人:Haihui Jiang
  • 数据来源: OTHERS
  • 论文编号:OTHERS20190383
  • 发表时间:2016-10-01

2016-10-01

已发表文章

发表杂志:J Neurosurg

发表类型: Research Article

影响因子(IF): 5.115

PMID: 26771849 Pubmed原文链接 全文下载

主要研究背景及目的

方法

A total of 30 samples from 16 male and 14 female patients (median age of 46.5 years) with a histological  diagnosis of primary anaplastic oligodendroglioma (AO) were collected in the study. The immunofluorescence technique  was used to identify vascular ECs, and the 1p/19q status was detected with fluorescence in situ hybridization. KaplanMeier plots were compared using the log-rank method.

结论

1p/19q co-deletion and polysomy can be also found in the ECs of AO, which suggests that the ECs are, in part, tumor related and reflect a novel aspect of tumor angiogenesis.

主要结果