国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Magnetic resonance angiography signal intensity as a marker of hemodynamic impairment in intracranial arterial stenosis
第一作者：Xinyi Leng
通讯作者：Ka Sing Wong
基本信息
- 负责人：Xinyi Leng
- 数据来源： CICAS
- 论文编号：CICAS20150087
- 发表时间：2013-11-26
2013-11-26
已发表文章
主要研究背景及目的
BACKGROUND: Intracranial arterial stenosis (ICAS) is the predominant cause of ischemic stroke and transient ischemic attack in Asia. Change of signal intensities (SI) across an ICAS on magnetic resonance angiography (MRA) may reflect its hemodynamic severity. METHODS: In-patients with a symptomatic single ICAS detected on 3D time-of-flight MRA were recruited from 2 hospitals. Baseline and 1-year follow-up data were collected. Signal intensity ratio (SIR) [ = (mean post-stenotic SI -mean background SI)/(mean pre-stenotic SI - mean background SI)] was evaluated on baseline MRA to represent change of SIs across an ICAS. Acute infarct volume was measured on baseline diffusion-weighted images (DWI). Relationships between SIR and baseline characteristics as well as 1y outcomes were evaluated.