Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Prognostic value of inflammatory mediators in 1-year outcome of acute ischemic stroke with middle cerebral artery stenosis

First author：Xiping Gong

Corresponding author：Yongjun Wang

essential_information

  • Person in charge：Xiping Gong
  • Data Sources： CICAS
  • Number of papers：CICAS20150088
  • Published time：2013-07-15

2013-07-15

Published articles

Journal：Mediators Inflamm

Publication type: Original Contributions

IF(IF): 3.236

PMID: 3760102 Link To Pubmed

Background And Purpose

BACKGROUND AND PURPOSE: Inflammation exists in inception, progression, and reperfusion of acute ischemic stroke. Insightful understanding of correlation in inflammatory mediators and stroke severity with intracranial artery stenosis may improve rational stroke therapy. METHODS: We prospectively recruited 977 patients with acute noncardioembolic ischemic stroke with MCA stenosis by MRA as none to mild (<50%), moderate (50-69%), severe (70-99%), or occlusive (100%). The peripheral levels of WBC, homocysteine (HCY), and high sensitivity C-reactive protein (hs-CRP) were recorded. All patients were assessed of 1-year outcome by mRS as favorable (0-2) or poor (3-6).

Method

Conclusion

Main results