Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
A comparative study of the amount of alpha-synuclein in ischemic stroke and Parkinson's disease.
First author：Huiqing Zhao
Corresponding author：Tao Feng
essential_information
- Person in charge：Huiqing Zhao
- Data Sources： OTHERS
- Number of papers：OTHERS20190417
- Published time：2016-05-01
2016-05-01
Published articles
Journal：Neurol Sci
Publication type: Original Article
IF(IF): 3.307
PMID: 26829934 Link To Pubmed Full text Download
Background And Purpose
Method
86 ischemic stroke, 100 PD, and 102 healthy cases were enrolled in the present study. Total protein amount in the red blood cells were quantified by BCA assay using spectrophotometer. Levels of oligomeric form of a-synuclein were characterized by a sandwich ELISA. Analysis of correlation analysis and receiver operating characteristic curve were conducted.
Conclusion
The levels of oligomeric form of a-synuclein of red blood cells in ischemic stroke and Parkinson’s disease patients were both significant higher than normal people. And the level of oligomeric form asynuclein showed a potential for diagnosis of ischemic stroke in clinic.