国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

A comparative study of the amount of alpha-synuclein in ischemic stroke and Parkinson's disease.

第一作者：Huiqing Zhao

通讯作者：Tao Feng

a-Synuclein Red blood cells Ischemice stroke Pa

基本信息

  • 负责人：Huiqing Zhao
  • 数据来源： OTHERS
  • 论文编号：OTHERS20190417
  • 发表时间：2016-05-01

2016-05-01

已发表文章

发表杂志：Neurol Sci

发表类型: Original Article

影响因子(IF): 3.307

PMID: 26829934 Pubmed原文链接 全文下载

主要研究背景及目的

方法

86 ischemic stroke, 100 PD, and 102 healthy cases were enrolled in the present study. Total protein amount in the red blood cells were quantified by BCA assay using spectrophotometer. Levels of oligomeric form of a-synuclein were characterized by a sandwich ELISA. Analysis of correlation analysis and receiver operating characteristic curve were conducted.

结论

The levels of oligomeric form of a-synuclein of red blood cells in ischemic stroke and Parkinson’s disease patients were both significant higher than normal people. And the level of oligomeric form asynuclein showed a potential for diagnosis of ischemic stroke in clinic.

主要结果