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Multi-mode CT in the evaluation of leptomeningeal collateral flow and the related factors: comparing with digital subtraction angiography.

First author：Xin Liu

Corresponding author：Yongjun Wang

Collateral circulation Ischemic stroke Multi-CT

essential_information

  • Person in charge：Xin Liu
  • Data Sources： OTHERS
  • Number of papers：OTHERS20190422
  • Published time：2016-06-01

2016-06-01

Published articles

Journal：Neurol Res

Publication type: Research Article

IF(IF): 2.448

PMID: 27320244 Link To Pubmed Full text Download

Background And Purpose

Method

Collateral status was assessed using a computed tomography angiography (CTA) source image (CTASI) based and digital subtraction angiography (DSA) based assessment system. CTP maps were quantitatively analyzed. CBF, CBV, MTT, and TTP were calculated within the hypoperfusion and in the equivalent region of unaffected hemisphere. ASTIN-ASN system based on DSA and leptomeningeal collaterals (LMC) system based on CTA were adopted separately, and the intra-rater and inter-rater were determined by Kappa testing. Receiver Operating Characteristic (ROC) curves were used to analyze the relationship between CTP quantitative parameters and DSA. The related factors of collateral flow were also explored in this study.

Conclusion

Our data showed that multi-mode CT score has a high value in predicting leptomeningeal collateral flow in ischemic stroke.

Main results

Collateral status was assessed using a computed tomography angiography (CTA) source image (CTA-SI) based and digital subtraction angiography (DSA) based assessment system. CTP maps were quantitatively analyzed. CBF, CBV, MTT, and TTP were calculated within the hypoperfusion and in the equivalent region of unaffected hemisphere. ASTIN-ASN system based on DSA and leptomeningeal collaterals (LMC) system based on CTA were adopted separately, and the intra-rater and inter-rater were determined by Kappa testing. Receiver Operating Characteristic (ROC) curves were used to analyze the relationship between CTP quantitative parameters and DSA. The related factors of collateral flow were also explored in this study.