国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Multi-mode CT in the evaluation of leptomeningeal collateral flow and the related factors: comparing with digital subtraction angiography.
第一作者：Xin Liu
通讯作者：Yongjun Wang
2016-06-01
已发表文章
主要研究背景及目的
方法
Collateral status was assessed using a computed tomography angiography (CTA) source image (CTASI) based and digital subtraction angiography (DSA) based assessment system. CTP maps were quantitatively analyzed. CBF, CBV, MTT, and TTP were calculated within the hypoperfusion and in the equivalent region of unaffected hemisphere. ASTIN-ASN system based on DSA and leptomeningeal collaterals (LMC) system based on CTA were adopted separately, and the intra-rater and inter-rater were determined by Kappa testing. Receiver Operating Characteristic (ROC) curves were used to analyze the relationship between CTP quantitative parameters and DSA. The related factors of collateral flow were also explored in this study.
结论
Our data showed that multi-mode CT score has a high value in predicting leptomeningeal collateral flow in ischemic stroke.
主要结果
Collateral status was assessed using a computed tomography angiography (CTA) source image (CTA-SI) based and digital subtraction angiography (DSA) based assessment system. CTP maps were quantitatively analyzed. CBF, CBV, MTT, and TTP were calculated within the hypoperfusion and in the equivalent region of unaffected hemisphere. ASTIN-ASN system based on DSA and leptomeningeal collaterals (LMC) system based on CTA were adopted separately, and the intra-rater and inter-rater were determined by Kappa testing. Receiver Operating Characteristic (ROC) curves were used to analyze the relationship between CTP quantitative parameters and DSA. The related factors of collateral flow were also explored in this study.