国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Apolipoprotein E epsilon4 Allele was Associated With Nonlesional Mesial Temporal Lobe Epilepsy in Han Chinese Population.

第一作者：Zhimei Li

通讯作者：Tao Cui

APOE = apolipoprotein E FC = febrile convulsion

基本信息

  • 负责人：Zhimei Li
  • 数据来源： OTHERS
  • 论文编号：OTHERS20190427
  • 发表时间：2016-01-01

2016-01-01

已发表文章

发表杂志：Medicine (Baltimore)

发表类型: Observational Study

影响因子(IF): 1.87

PMID: 26945380 Pubmed原文链接 全文下载

主要研究背景及目的

方法

The study consisted of total 308 NLMTLE patients and 302 controls in Han Chinese. The APOE polymorphisms were genotyped using polymerase chain reaction (PCR) DNA sequencing. We compared the frequency of APOEe4 allele and carrying status between NLMTLE patients and control subjects to test for the association of APOEe4 allele with NLMTLE clinical status

结论

Our study provided an evidence that APOEe4 allele was a possible risk factor for NLMTLE, and further study with a larger sample is needed to warrant this finding.

主要结果