Proposal and Validation of a Basic Progression Scoring System for Patients with Skull Base Chordoma.
First author:Junpeng Ma, Kaibing Tian
Corresponding author:Junting Zhang
2017-02-01
Journal:World Neurosurg
Publication type: Research Article
IF(IF): 2.104
PMID: 27998723 Link To Pubmed Full text Download
All patients (n [ 170) undergoing operation for skull base chordoma were classified randomly into a training (n [ 113) or validation set (n [ 57). In the training set, adverse factors for progression were analyzed by univariate and multivariate analyses. Significant independent factors were included into the scoring system. Scores for each risk category were allocated 1 point and each protection category 0 point. Three prognostic groups wereformed on the basis of total score. The same scoring and grouping dispositions were made in the validation set. Analyses of the differences among the 3 groups in individual sets with regard to recurrence and the comparisons between the corresponding prognostic groups of both sets were all carried out by the Kaplan-Meier method
The basic progression scoring system for patients with skull base chordoma is valid and reproducible.