Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Proposal and Validation of a Basic Progression Scoring System for Patients with Skull Base Chordoma.

First author:Junpeng Ma, Kaibing Tian

Corresponding author:Junting Zhang

Chordoma Prognosis Progression Scoring system S

essential_information

2017-02-01

Published articles

Journal:World Neurosurg

Publication type: Research Article

IF(IF): 2.104

PMID: 27998723 Link To Pubmed Full text Download

Background And Purpose

Method

All patients (n [ 170) undergoing operation for skull base chordoma were classified randomly into a training (n [ 113) or validation set (n [ 57). In the training set, adverse factors for progression were analyzed by univariate and multivariate analyses. Significant independent factors were included into the scoring system. Scores for each risk category were allocated 1 point and each protection category 0 point. Three prognostic groups wereformed on the basis of total score. The same scoring and grouping dispositions were made in the validation set. Analyses of the differences among the 3 groups in individual sets with regard to recurrence and the comparisons between the corresponding prognostic groups of both sets were all carried out by the Kaplan-Meier method

Conclusion

The basic progression scoring system for patients with skull base chordoma is valid and reproducible.

Main results