Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Prediction of High-Grade Pediatric Meningiomas: Magnetic Resonance Imaging Features Based on T1-Weighted, T2-Weighted, and Contrast-Enhanced T1-Weighted Images.
First author：Hao Li
Corresponding author：Yong Cao, Jizong Zhao
essential_information
2016-07-01
Published articles
Journal：World Neurosurgery
Publication type: Research Article
IF(IF): 2.104
PMID: 27046015 Link To Pubmed Full text Download
Background And Purpose
Method
We retrospectively reviewed preoperative magnetic resonance imaging features and histopathologic diagnosis according to the 2007 World Health Organization classification system for intracranial tumors of 79 pediatric meningiomas from 2005 to 2015. World Health Organization grade II and III meningiomas were defined as high-grade meningiomas. The relationship between the radiologic findings and incidence of high-grade meningiomas was assessed initially with univariate analysis and then corrected by multivariate analysis.
Conclusion
In pediatric patients, meningiomas with an unclear tumor-brain interface, lateral location, and narrow base on preoperative magnetic resonance imaging are more likely to be high-grade meningiomas. Our results may be helpful in decision making regarding therapeutic strategies for pediatric patients with meningiomas.
Main results
We retrospectively reviewed preoperative magnetic resonance imaging features and histopathologic diagnosis according to the 2007 World Health Organization classification system for intracranial tumors of 79 pediatric meningiomas from 2005 to 2015. World Health Organization grade II and III meningiomas were defined as high-grade meningiomas. The relationship between the radiologic findings and incidence of high-grade meningiomas was assessed initially with univariate analysis and then corrected by multivariate analysis.