Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Surgical Treatment of Cavernous Malformations Involving the Posterior Limb of the Internal Capsule: Utility and Predictive Value of Preoperative Diffusion Tensor Imaging.
First author：Fuxin Lin, Jun Wu
Corresponding author：Yong Cao
essential_information
- Person in charge：Fuxin Lin, Jun Wu
- Data Sources： OTHERS
- Number of papers：OTHERS20190454
- Published time：2016-04-01
2016-04-01
Published articles
Journal：World Neurosurgery
Publication type: Research Article
IF(IF): 2.104
PMID: 26561439 Link To Pubmed Full text Download
Background And Purpose
Method
Patients with PLIC-CMs who were surgically treated between September 2012 and June 2015 were reviewed. All patients underwent preoperative DTI. Three major fiber tracts were selected for evaluation: 1) corticospinal tract (CST); 2) arcuate fasciculus (AF); and 3) optic radiation (OR). The utility of preoperative DTI for surgical approach selection and intraoperative navigation was documented. An involvement grading system of the major fibers was applied to determine the predictive value of preoperative DTI. A last modified Rankin Scale (mRS) score of 0-2 was considered a good outcome, and a last mRS >2 was considered a poor outcome.
Conclusion
Preoperative DTI may be a promising tool to determine the surgical approach and predict the surgical outcomes in patients with PLIC-CMs.
Main results
Thirteen patients with 13 PLIC-CMs were reviewed in this study. All the lesions were radically resected via the corridor formed by CST, AF, and OR. None of the patents suffered from mRS >3, and 7 patients (53.8%) got good outcomes at the last clinic visit. The difference between the preoperative mRS scores and last mRS scores was not significant (P = 0.673). The involvement grade of the fiber tracts was significantly associated with the surgical outcome (P = 0.011).