国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Bone invasiveness is associated with prognosis in clivus chordomas.

第一作者:Ke Wang

通讯作者:Junting Zhang

Clivus chordoma; Growth pattern; Prognosis

基本信息

  • 负责人:Ke Wang
  • 数据来源: OTHERS
  • 论文编号:OTHERS20190459
  • 发表时间:2016-03-30

2016-03-30

已发表文章

发表杂志:Journal of Clinical Neuroscience

发表类型: Research Article

影响因子(IF): 1.961

PMID: 26810468 Pubmed原文链接 全文下载

主要研究背景及目的

方法

Clinical data, MRI, CT scans and follow-up data were examined, and the bone invasiveness of the chordoma was classified into two growth patterns (endophytic and exophytic) which were analyzed with regard to prognosis.

结论

Chordomas with an exophytic growth pattern were more likely to recur than those with an endophytic growth pattern, and the surgical approach can be tailored according to each growth pattern.

主要结果

The overall survival rate was 78.9% with radical surgery and adjuvant radiation, with a mean follow-up of 44.5months. There were 12 patients in the endophytic group and seven in the exophytic group, and the exophytic group exhibited a higher recurrence rate than the endophytic group (p=0.006).