国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Geographic and sex difference in the distribution of intracranial atherosclerosis in China
第一作者：Pu Yuehua
通讯作者：Wang Yongjun
2013-06-11
已发表文章
发表杂志：Stroke
发表类型: Original Contributions
影响因子(IF): 7.914
PMID:
主要研究背景及目的
BACKGROUND AND PURPOSE: Geographic variation and sex difference in the distribution of intracranial atherosclerosis (ICAS) have not been fully discussed before in Chinese patients with cerebral ischemia. We performed this study with the aim to investigate geographic and sex difference in the distribution of ICAS in China. METHODS: In this prospective multicenter study, we evaluated 2864 consecutive patients who experienced an acute cerebral ischemia within 7 days of symptom onset in 22 hospitals in China. All the inclusive patients underwent 3-dimensional time-of-flight MR angiography and duplex color Doppler ultrasound or contrast-enhanced MR angiography to document the presence of intracranial or extracranial stenosis. Intracranial large-artery atherosclerosis was defined as >/=50% diameter reduction on MR angiography.