Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Geographic and sex difference in the distribution of intracranial atherosclerosis in China

First author：Pu Yuehua

Corresponding author：Wang Yongjun

essential_information

  • Person in charge：Pu Yuehua
  • Data Sources： CICAS
  • Number of papers：CICAS20150093
  • Published time：2013-06-11

2013-06-11

Published articles

Journal：Stroke

Publication type: Original Contributions

IF(IF): 7.914

PMID:

Background And Purpose

BACKGROUND AND PURPOSE: Geographic variation and sex difference in the distribution of intracranial atherosclerosis (ICAS) have not been fully discussed before in Chinese patients with cerebral ischemia. We performed this study with the aim to investigate geographic and sex difference in the distribution of ICAS in China. METHODS: In this prospective multicenter study, we evaluated 2864 consecutive patients who experienced an acute cerebral ischemia within 7 days of symptom onset in 22 hospitals in China. All the inclusive patients underwent 3-dimensional time-of-flight MR angiography and duplex color Doppler ultrasound or contrast-enhanced MR angiography to document the presence of intracranial or extracranial stenosis. Intracranial large-artery atherosclerosis was defined as >/=50% diameter reduction on MR angiography.

Method

Conclusion

Main results