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Regional cerebral blood flow correlates eating abnormalities in frontotemporal dementia
First author：Zhou Zhi,Li Xudong
Corresponding author：Zheng Xiaoyun
essential_information
- Person in charge：Zhou Zhi,Li Xudong
- Data Sources： OTHERS
- Number of papers：OTHERS20190839
- Published time：2019-04-30
2019-04-30
Published articles
Journal：Neurological sciences
Publication type: Original Article
IF(IF): 3.307
PMID: 31041612 Link To Pubmed Full text Download
Background And Purpose
Method
A group of FTD patients (43 bvFTD, 29 svPPA) underwent single-photon emission CT (SPECT) to measure the region cerebral blood flow (rCBF). The Cambridge Behavioral Inventory (CBI) was used to measure the eating abnormalities. A whole-brain voxel-based correlation between eating abnormalities and rCBF was investigated.
Conclusion
These findings showed that either different symptoms in the same subtype or the same symptom in different subtypes of FTD may be correlated with different regions, indicating different neural mechanisms behind them.
Main results
In bvFTD, the sweet preference was correlated with decreased rCBF in the bilateral gyrus rectus and temporal pole, and eating the same food was correlated with the left ventral anterior cingulate cortex. In svPPA, decreased rCBF in the left inferior temporal gyrus was correlated with eating the same food.