国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

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Regional cerebral blood flow correlates eating abnormalities in frontotemporal dementia

第一作者：Zhou Zhi,Li Xudong

通讯作者：Zheng Xiaoyun

Eating abnormalities; Frontotemporal dementia; Reg

基本信息

2019-04-30

已发表文章

发表杂志：Neurological sciences

发表类型: Original Article

影响因子(IF): 3.307

PMID: 31041612 Pubmed原文链接 全文下载

主要研究背景及目的

方法

A group of FTD patients (43 bvFTD, 29 svPPA) underwent single-photon emission CT (SPECT) to measure the region cerebral blood flow (rCBF). The Cambridge Behavioral Inventory (CBI) was used to measure the eating abnormalities. A whole-brain voxel-based correlation between eating abnormalities and rCBF was investigated.

结论

These findings showed that either different symptoms in the same subtype or the same symptom in different subtypes of FTD may be correlated with different regions, indicating different neural mechanisms behind them.

主要结果

In bvFTD, the sweet preference was correlated with decreased rCBF in the bilateral gyrus rectus and temporal pole, and eating the same food was correlated with the left ventral anterior cingulate cortex. In svPPA, decreased rCBF in the left inferior temporal gyrus was correlated with eating the same food.