Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Adipose tissue specific insulin resistance and prognosis of nondiabetic patients with ischemic stroke
First author：Qi Zhou
Corresponding author：Yuesong Pan
essential_information
2023-12-02
Published articles
Journal：Diabetology & Metabolic Syndrome
Publication type: Original Contributions
IF(IF): 4.8
PMID: 38041145 Link To Pubmed Full text Download
Background And Purpose
Insulin resistance is linked to atherosclerotic cardiovascular diseases and stroke, whereas less is known about adipose tissue-specific insulin resistance and outcomes after ischemic stroke. This study aimed to estimate the association between adipose tissue-specific insulin resistance and the prognosis of nondiabetic patients with ischemic stroke.
Method
We assessed the association between Adipo-IR and risk of prognosis by multivariable Cox/logistic regression models adjusted for potential covariates.
Conclusion
These findings suggest that adipose tissue specific insulin resistance is independently associated with recurrent stroke and combined vascular events after acute ischemic stroke in nondiabetic patients.