国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Adipose tissue specific insulin resistance and prognosis of nondiabetic patients with ischemic stroke

第一作者:Qi Zhou

通讯作者:Yuesong Pan

Adipose tissue Insulin resistance Metabolism Risk Stroke

基本信息

  • 负责人:Qi Zhou
  • 数据来源: CNSR-Ⅲ
  • 论文编号:CNSR-Ⅲ20220178
  • 发表时间:2023-12-02

2023-12-02

已发表文章

发表杂志:Diabetology & Metabolic Syndrome

发表类型: Original Contributions

影响因子(IF): 4.8

PMID: 38041145 Pubmed原文链接 全文下载

主要研究背景及目的

Insulin resistance is linked to atherosclerotic cardiovascular diseases and stroke, whereas less is known about adipose tissue-specific insulin resistance and outcomes after ischemic stroke. This study aimed to estimate the association between adipose tissue-specific insulin resistance and the prognosis of nondiabetic patients with ischemic stroke.

方法

We assessed the association between Adipo-IR and risk of prognosis by multivariable Cox/logistic regression models adjusted for potential covariates.

结论

These findings suggest that adipose tissue specific insulin resistance is independently associated with recurrent stroke and combined vascular events after acute ischemic stroke in nondiabetic patients.

主要结果