国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Relationship between time-updated proteinuria and risk of stroke in general population with different glucose level

第一作者：Anxin Wang,Jia Zhang

通讯作者：Xingquan Zhao, Yongjun Wang

diabetes mellitus ■ prediabetes ■ stroke ■ time-de

基本信息

2020-06-14

已发表文章

发表杂志：Journal of the American Heart Association

发表类型: Original Research

影响因子(IF): 5.501

PMID: 10.1161/JAHA.120.015776 Pubmed原文链接 全文下载

主要研究背景及目的

The common ground of previous studies were performed at baseline or at the end point of proteinuria, which did not take into account changes over time. Persistent status of proteinuria was seldom evaluated. Proteinuria also was associated with the status of glucose level. So, this study aimed to evaluate the relationship between time-updated proteinuria and risk of stroke among a large cohort of general Chinese population with different glucose level.

方法

time-updated Cox regression model

结论

Time-dependent proteinuria is an independent risk factor of stroke, especially in the normoglycemia and prediabetes populations.

主要结果