Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
The infarct location predicts the outcome of single small subcortical infarction in the territory of the middle cerebral artery
First author：Xiaomeng Yang
Corresponding author：Yongjun Wang
essential_information
- Person in charge：Xiaomeng Yang
- Data Sources： CICAS
- Number of papers：CICAS20190095
- Published time：2014-02-01
2014-02-01
Published articles
Journal： Journal of stroke and cerebrovascular diseases
Publication type: Original Contributions
IF(IF): 1.599
PMID: 24739591 Link To Pubmed Full text Download
Background And Purpose
Single small subcortical infarction (SSSI) in the territory of the middle cerebral artery (MCA) may be classified as proximal SSSI (pSSSI) or distal SSSI (dSSSI) according to its extension to the MCA. We sought to investigate the outcome of different types of SSSIs
Method
We assessed 177 patients who had an SSSI (67 pSSSI and 110 dSSSI) in the perforator territory of MCA. The clinical characteristics, neurologic status (initial National Institutes of Health Stroke Scale score at admission and modified Rankin Scale [mRS] score at 1 year), and clinical treatments at 1 year were evaluated.
Conclusion
SSSI has a heterogeneous outcome at 1 year according to the lesion location.
Main results
Among the 177 patients, 130 had favorable (mRS score # 1) and 41 had unfavorable outcome (mRS score $ 2) at 1 year, dSSSI had higher mRS than pSSSI at 1 year (1 [0-2] versus 0 [0-1]; P 5.013). The age (odds ratio [OR] 1.049, 95% confidence interval [CI] 1.002-1.098; P 5.041) and distal location of the lesion (OR 2.687, 95% CI 1.039-6.948; P 5.042) were found to be independent risk factors of 1-year unfavorable outcome of SSSIs.