国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
The infarct location predicts the outcome of single small subcortical infarction in the territory of the middle cerebral artery
第一作者：Xiaomeng Yang
通讯作者：Yongjun Wang
基本信息
- 负责人：Xiaomeng Yang
- 数据来源： CICAS
- 论文编号：CICAS20190095
- 发表时间：2014-02-01
2014-02-01
已发表文章
发表杂志： Journal of stroke and cerebrovascular diseases
发表类型: Original Contributions
影响因子(IF): 1.599
PMID: 24739591 Pubmed原文链接 全文下载
主要研究背景及目的
Single small subcortical infarction (SSSI) in the territory of the middle cerebral artery (MCA) may be classified as proximal SSSI (pSSSI) or distal SSSI (dSSSI) according to its extension to the MCA. We sought to investigate the outcome of different types of SSSIs
方法
We assessed 177 patients who had an SSSI (67 pSSSI and 110 dSSSI) in the perforator territory of MCA. The clinical characteristics, neurologic status (initial National Institutes of Health Stroke Scale score at admission and modified Rankin Scale [mRS] score at 1 year), and clinical treatments at 1 year were evaluated.
结论
SSSI has a heterogeneous outcome at 1 year according to the lesion location.
主要结果
Among the 177 patients, 130 had favorable (mRS score # 1) and 41 had unfavorable outcome (mRS score $ 2) at 1 year, dSSSI had higher mRS than pSSSI at 1 year (1 [0-2] versus 0 [0-1]; P 5.013). The age (odds ratio [OR] 1.049, 95% confidence interval [CI] 1.002-1.098; P 5.041) and distal location of the lesion (OR 2.687, 95% CI 1.039-6.948; P 5.042) were found to be independent risk factors of 1-year unfavorable outcome of SSSIs.