Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
In-hospital complications affect short-term and long-term mortality in ICH: a prospective cohort study
First author：Yaqing Zhang
Corresponding author：Penglian Wang,Xingquan Zhao
essential_information
- Person in charge：Yaqing Zhang
- Data Sources： CNSR-I
- Number of papers：CNSR-I20190110
- Published time：2020-10-29
2020-10-29
Published articles
Journal：stroke and vascular neurology，haemorrhage
Publication type: Original Contributions
IF(IF): 4.765
PMID: 33122255 Link To Pubmed Full text Download
Background And Purpose
Stroke remains a major cause of death and long-term disability worldwide. In-hospital complications are associated with poorer clinical outcomes for stroke patients after disease onset.However,few studies from China have reperted the effect of these complications on the mortality of patients with intracerebral hemorrhage.In this work,the CNSR study,we investigated the relationship between in-hospital complications and outcomes of patients with intracerebral hemorrhage.
Method
Methods This study collected data on patients over 18 years old with spontaneous ICH from 132 Chinese clinical centres across 32 provinces and four municipalities (Hong Kong included), from September 2007 to August 2008. Data on patient complications, death and other information were acquired through paper-based registry forms. Using multivariable logistic regression, the association of medical complications with stroke outcomes was evaluated.
Conclusion
The results revealed that the short-term and long-term mortality of patients with spontaneous ICH in China was significantly associated with their in-hospital medical complications
Main results
Of 3255 patients with spontaneous ICH, 878 (26.97%) had in-hospital medical complications. In hospital medical complications were independent risk factors for death during the hospitalisation (adjusted OR 4.41, 95% CI 3.18 to 6.12), at 3 months (adjusted OR 2.18, 95% CI 1.70 to 2.80), 6 months (adjusted OR 1.84, 95% CI 1.45 to 2.34) and 12 months (adjusted OR 1.59, 95% CI 1.26 to 2.01) after spontaneous ICH.