国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
In-hospital complications affect short-term and long-term mortality in ICH: a prospective cohort study
第一作者：Yaqing Zhang
基本信息
- 负责人：Yaqing Zhang
- 数据来源： CNSR-I
- 论文编号：CNSR-I20190110
- 发表时间：2020-10-29
2020-10-29
已发表文章
发表杂志：stroke and vascular neurology，haemorrhage
发表类型: Original Contributions
影响因子(IF): 4.765
PMID: 33122255 Pubmed原文链接 全文下载
主要研究背景及目的
Stroke remains a major cause of death and long-term disability worldwide. In-hospital complications are associated with poorer clinical outcomes for stroke patients after disease onset.However,few studies from China have reperted the effect of these complications on the mortality of patients with intracerebral hemorrhage.In this work,the CNSR study,we investigated the relationship between in-hospital complications and outcomes of patients with intracerebral hemorrhage.
方法
Methods This study collected data on patients over 18 years old with spontaneous ICH from 132 Chinese clinical centres across 32 provinces and four municipalities (Hong Kong included), from September 2007 to August 2008. Data on patient complications, death and other information were acquired through paper-based registry forms. Using multivariable logistic regression, the association of medical complications with stroke outcomes was evaluated.
结论
The results revealed that the short-term and long-term mortality of patients with spontaneous ICH in China was significantly associated with their in-hospital medical complications
主要结果
Of 3255 patients with spontaneous ICH, 878 (26.97%) had in-hospital medical complications. In hospital medical complications were independent risk factors for death during the hospitalisation (adjusted OR 4.41, 95% CI 3.18 to 6.12), at 3 months (adjusted OR 2.18, 95% CI 1.70 to 2.80), 6 months (adjusted OR 1.84, 95% CI 1.45 to 2.34) and 12 months (adjusted OR 1.59, 95% CI 1.26 to 2.01) after spontaneous ICH.