国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Integrative proteomics and transcriptomics revealed that activation of the IL-6R/JAK2/STAT3/MMP9 signaling pathway is correlated with invasion of pituitary null cell adenomas.

第一作者：Jie Feng, Sheng-Yuan Yu

通讯作者：Ya-Zhuo Zhang

Pituitary adenomas Null cell adenomas Invasion IL-

基本信息

2016-11-15

已发表文章

发表杂志：Mol Cell Endocrinol

发表类型: Research Article

影响因子(IF): 4.102

PMID: 27465831 Pubmed原文链接 全文下载

主要研究背景及目的

方法

Total ribonucleic acid (RNA) extraction Microarray hybridization Protein preparation and nanoLC-MS/MS analysis Reverse transcription and quantitative real-time polymerase chain reaction (qRT-PCR) analysis Immunohistochemical staining Bioinformatics analysis and statistics

结论

Our data suggest that overactivation of the IL-6R/JAK2/STAT3/MMP9 pathway is critical for the invasion of PNCAs.

主要结果