Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Factors for tumor progression in patients with skull base chordoma.
First author：Linsheng Wang
Corresponding author：Junting Zhang
essential_information
- Person in charge：Linsheng Wang
- Data Sources： OTHERS
- Number of papers：OTHERS20190398
- Published time：2016-09-01
2016-09-01
Published articles
Journal：Cancer Medicine
Publication type: Research Article
IF(IF): 4.452
PMID: 27546605 Link To Pubmed Full text Download
Background And Purpose
Method
Data of 229 patients with skull base chordoma treated by one institution between 2005 and 2014 were retrieved and grouped as primary and recurrent. Kaplan–Meier survival of progression was estimated, taking competing risks into account. Multivariable Cox regression was used to investigate survival predictors.
Conclusion
we found that factors for tumor progression demonstrated some difference between primary and recurrent cases. We also found that a tendency of accelerating progress existed after tumor recurrence. The nomogram of tumor progression, which was consisted by factors of initial symptom, biological behavior of bone invasion, pathological characteristics, and functional status, was well established for risk stratification of primary cases.