国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Factors for tumor progression in patients with skull base chordoma.

第一作者：Linsheng Wang

通讯作者：Junting Zhang

Chordoma nomogram prognosis progression-free su

基本信息

  • 负责人：Linsheng Wang
  • 数据来源： OTHERS
  • 论文编号：OTHERS20190398
  • 发表时间：2016-09-01

2016-09-01

已发表文章

发表杂志：Cancer Medicine

发表类型: Research Article

影响因子(IF): 4.452

PMID: 27546605 Pubmed原文链接 全文下载

主要研究背景及目的

方法

Data of 229 patients with skull base chordoma treated by one institution between 2005 and 2014 were retrieved and grouped as primary and recurrent. Kaplan–Meier survival of progression was estimated, taking competing risks into account. Multivariable Cox regression was used to investigate survival predictors.

结论

we found that factors for tumor progression demonstrated some difference between primary and recurrent cases. We also found that a tendency of accelerating progress existed after tumor recurrence. The nomogram of tumor progression, which was consisted by factors of initial symptom, biological behavior of bone invasion, pathological characteristics, and functional status, was well established for risk stratification of primary cases.

主要结果