Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
The diagnostic value of cerebrospinal fluid lactate for post-neurosurgical bacterial meningitis: a meta-analysis.
First author：Xiong Xiao
Corresponding author：Nan Ji
essential_information
- Person in charge：Xiong Xiao
- Data Sources： OTHERS
- Number of papers：OTHERS20190414
- Published time：2016-09-13
2016-09-13
Published articles
Journal：Bmc Infectious Diseases
Publication type: Meta Analysis
IF(IF): 3.09
PMID: 27618955 Link To Pubmed Full text Download
Background And Purpose
Method
We retrieved studies that investigated the diagnostic value of CSF lactate for the diagnosis of postneurosurgical bacterial meningitis by searching PubMed, EBSCO, the Cochrane Library and ClinicalTrials.gov. All these databases were searched from inception to November 2015. We used Quality Assessment of Diagnostic Accuracy Studies (QUADAS), a tool for the quality assessment of diagnostic accuracy, to evaluate the quality of the included studies. The Meta-DiSc 1.4 and Review Manager 5.3 software programs were used to analyze the included studies. Forest plots and summary receiver operating characteristics (SROC) curves were also drawn.
Conclusion
The meta-analysis indicated that the CSF lactate concentration has relatively high sensitivity and specificity for the diagnosis of post-neurosurgical bacterial meningitis and thus has relatively good efficacy