国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

The diagnostic value of cerebrospinal fluid lactate for post-neurosurgical bacterial meningitis: a meta-analysis.

第一作者：Xiong Xiao

通讯作者：Nan Ji

基本信息

  • 负责人：Xiong Xiao
  • 数据来源： OTHERS
  • 论文编号：OTHERS20190414
  • 发表时间：2016-09-13

2016-09-13

已发表文章

发表杂志：Bmc Infectious Diseases

发表类型: Meta Analysis

影响因子(IF): 3.09

PMID: 27618955 Pubmed原文链接 全文下载

主要研究背景及目的

方法

We retrieved studies that investigated the diagnostic value of CSF lactate for the diagnosis of postneurosurgical bacterial meningitis by searching PubMed, EBSCO, the Cochrane Library and ClinicalTrials.gov. All these databases were searched from inception to November 2015. We used Quality Assessment of Diagnostic Accuracy Studies (QUADAS), a tool for the quality assessment of diagnostic accuracy, to evaluate the quality of the included studies. The Meta-DiSc 1.4 and Review Manager 5.3 software programs were used to analyze the included studies. Forest plots and summary receiver operating characteristics (SROC) curves were also drawn.

结论

The meta-analysis indicated that the CSF lactate concentration has relatively high sensitivity and specificity for the diagnosis of post-neurosurgical bacterial meningitis and thus has relatively good efficacy

主要结果