Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Analysis of Clinical Features and Outcomes of Skull Base Chordoma in Different Age-Groups.
First author：Kaibing Tian
Corresponding author：Junting Zhang
essential_information
- Person in charge：Kaibing Tian
- Data Sources： OTHERS
- Number of papers：OTHERS20190435
- Published time：2016-08-01
2016-08-01
Published articles
Journal：World Neurosurgery
Publication type: Original Article
IF(IF): 2.104
PMID: 27237421 Link To Pubmed Full text Download
Background And Purpose
Method
In this retrospective study, patients with SBC who underwent surgical treatment between February 2005 and December 2014 were included. Clinical features were recorded, including the signal intensity ratio of tumor to brain stem in T1 (RT1), T2 (RT2), and enhanced T1 (REN) sequences in primary patients with complete preoperative magnetic resonance images. The clinical features and outcomes were compared between younger (£24 years) and older patients (‡25 years).
Conclusion
In younger patients, there were more SBCs located in the occipitocervical regions, and younger patients tended to undergo more aggressive resection. The tumor signal intensity of younger patients with SBC was higher in T2 images but lower in enhanced T1 images. A younger age was a favorable factor for a longer progression-free survival and a good neurologic status at follow-up.
Main results
In this retrospective study, patients with SBC who underwent surgical treatment between February 2005 and December 2014 were included. Clinical features were recorded, including the signal intensity ratio of tumor to brain stem in T1 (RT1), T2 (RT2), and enhanced T1 (REN) sequences in primary patients with complete preoperative magnetic resonance images. The clinical features and outcomes were compared between younger (?24 years) and older patients (?25 years).