国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Analysis of Clinical Features and Outcomes of Skull Base Chordoma in Different Age-Groups.

第一作者：Kaibing Tian

通讯作者：Junting Zhang

Age Clinical feature Outcome Skull base chordom

基本信息

  • 负责人：Kaibing Tian
  • 数据来源： OTHERS
  • 论文编号：OTHERS20190435
  • 发表时间：2016-08-01

2016-08-01

已发表文章

发表杂志：World Neurosurgery

发表类型: Original Article

影响因子(IF): 2.104

PMID: 27237421 Pubmed原文链接 全文下载

主要研究背景及目的

方法

In this retrospective study, patients with SBC who underwent surgical treatment between February 2005 and December 2014 were included. Clinical features were recorded, including the signal intensity ratio of tumor to brain stem in T1 (RT1), T2 (RT2), and enhanced T1 (REN) sequences in primary patients with complete preoperative magnetic resonance images. The clinical features and outcomes were compared between younger (£24 years) and older patients (‡25 years).

结论

In younger patients, there were more SBCs located in the occipitocervical regions, and younger patients tended to undergo more aggressive resection. The tumor signal intensity of younger patients with SBC was higher in T2 images but lower in enhanced T1 images. A younger age was a favorable factor for a longer progression-free survival and a good neurologic status at follow-up.

主要结果

In this retrospective study, patients with SBC who underwent surgical treatment between February 2005 and December 2014 were included. Clinical features were recorded, including the signal intensity ratio of tumor to brain stem in T1 (RT1), T2 (RT2), and enhanced T1 (REN) sequences in primary patients with complete preoperative magnetic resonance images. The clinical features and outcomes were compared between younger (?24 years) and older patients (?25 years).